Matrix-Assisted Laser Desorption/Ionization (MALDI) Matrix Info


Moderator: Kevin Owens

Purpose
The purpose of this wiki is to serve as a location to collect various molecular and spectroscopic information about molecules commonly used as "matrices" in the matrix-assisted laser desorption/ionization technique. In order to allow the widest distribution of this information, open-source tools will be used whenever possible.

List of Matrix Molecules:
MA0001 DHB, 2,5-dihydroxybenzoic acid, gentisic acid
MA0002 CHCA, alpha-cyano-4-hydroxycinnamic acid
MA0003 dithranol, 1,8-dihydroxyanthracen-9(10H)-one
MA0004 sinapinic acid, SA, sinapic acid, 3,5-dimethoxy-4-hydroxycinnamic acid
MA0005 ferulic acid, FA, 3-methoxy-4-hydroxycinnamic acid
MA0006 THAP, 2,4,6-trihydroxyacetophenone
MA0007 HABA, 2-(4-hydroxyphenylazo)-benzoic acid
MA0008 IAA, trans-3-indoleacrylic acid,
MA0009 vanillic acid, 4-hydroxy-3-methoxybenzoic acid
MA0010 ATT, 6-aza-2-thiothymine
MA0011 ANP, 2-amino-4-methyl-5-nitropyridine
MA0012 4-NA, 4-nitroaniline
MA0013 1,5-DAN, 1,5-diaminonaphthalene

Matrix Molecules UV Table for samples in MeOH
Solid State Matrix Molecules UV Table

List of "Matrix-Like" Molecules:
ML0001 5-fluorosalicylic acid
ML0002 5-chlorosalicylic acid
ML0003 5-bromosalicylic acid
ML0004 5-iodosalicylic acid
ML0005 5-methylsalicylic acid
ML0006 5-aminosalicylic acid
ML0007 1,8-DAN, 1,8-diaminonaphthalene
Matrix-Like Molecules UV Table
Solid State Matrix-Like Molecules UV Table

Solvent Information
Solvent Information Some common solvent properties and links to Chemspider and Wikipedia

Molecular Information

Information about Collected Spectra
UV/visible/NIR Data Information about how both the solution and solid state UV/visible spectra of the matrix materials are collected.
Infrared Data Information about how the infrared absorption spectra of the matrix materials are collected.
MALDI Data Information about how the MALDI TOFMS spectra of the matrix materials are collected.

Descriptions
Jmol Preparation A short description of how to create the Jmol view of the molecule to include on the molecule information page.
Bruker Data Conversion A description of how to convert the native-Bruker FID format data to JCAMP format for viewing on-line using JSpecView. This is a several step process, including modification of the JCAMP files to add the instrument parameter and sample preparation details to complete the spectral documentation.
UV Data Conversion A description of how to convert data collected using the Perkin-Elmer UV Winlab software into a JCAMP.DX file that can be viewed online using JSpecView.

Additional Molecular Information Desired/Needed
To Do List Please indicate on the wiki "to do list" what other types of molecular or spectroscopic information is needed to facilitate MALDI research.